Metabolic Syndrome: To Be or Not To Be?

Metabolic syndrome: to be or not to be?

to be or not to be that’s the question-3

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Early repolarization syndrome- to be or not to be benign.

The early repolarization syndrome, particular electrocardiographic aspect defined as J point and concave ST segment elevation, interpreted by electrophysiologists as benign for over five decades, caused over the past three years many controversies. The trigger for controversy were the results of several, mostly retrospective, studies concluding that individuals with early repolarization syndrom...

ASK "to be, or not to be?".

“To be, or not to be? That is the question.” William Shakespeare, The Tragedy of Hamlet, Prince of Denmark (1599-1602). Viral infection triggers host defense mechanisms that include the production of type I interferon (IFN) and the induction of apoptosis. Type I IFN, such as IFN-α and IFN-β, establishes the antiviral state to inhibits viral replication within infected cells, whereas apoptosis o...

To be or not to be B7.

The activation of lymphocytes and development of adaptive immune responses is initiated by the engagement of TCRs by antigenic peptide-MHC complexes and shaped at the clonal level by both positive and negative costimulatory signals. The B7 family members are involved at several stages in this process. In this issue of the JCI, Vogt et al. show that the B7 family-related protein V-set and Ig dom...